Size
Mid-size interfaces are still small desktop boxes, with more connected at once. The Scarlett 4i4 3rd Gen adds two line inputs, four outputs and MIDI. The MOTU M4 adds a second pair of line inputs and four outputs. The Apollo Solo USB puts UAD DSP inside, so you can track through UA plug-ins as you record. Most of this size still runs on USB bus power, but the Apollo Solo USB needs its 12 V supply, so look for it in the photos. Count outputs as well as inputs if you run speakers and headphones.
5 models we cover.
Focusrite
USB$180–$290 typical ask
21 on eBay
Universal Audio
USB$500–$700 typical ask
20 on eBay
MOTU
USB$270–$300 typical ask
16 on eBay
PreSonus
USB$110–$150 typical ask
6 on eBay
PreSonus
USB$130–$200 typical ask
6 on eBay